Your patient-centered medical home, providing comprehensive, coordinated care right in your neighborhood. Main Street Physicians has you and your family covered, offering same day office visits, virtual visits, and hospital-based care. We also provide 24/7 access to your full medical chart, ensuring personalized care wherever you are. As your trusted partners, we’re helping build a healthier community one patient at a time.
Welcome to Main Street Physicians in Woodhaven, MI, where your well-being matters most and specialized care isn’t just something we say, it’s what we do every day. Dr. Christopher R. DeAngelis, a dedicated internal medicine physician with over 20 years of hands-on experience, takes time to listen, treat the whole person, and help guide your care through every stage of life. Whether you’re here for preventive care or more complex health needs, you’ll always get the time, attention, and respect you deserve. We care that’s thoughtful, skilled, and grounded in the community we proudly serve.
Visiting your doctor on a regular basis is key to a healthy life. Whether you're feeling the effects of the common cold or just coming in for a checkup, we want to make sure you have all the facts you need to make an educated decision.
Services we offer include:
Quick, reliable acute disease management for common illnesses like infections, colds, and minor health concerns when you need fast relief.
Focused chronic disease management plans that help you take control of long-term conditions and improve daily quality of life.
An annual checkup is your yearly health check-in, helping us track progress, spot concerns early, and keep you on course.
Our preventive health care services include screenings, vaccinations, and practical advice to help you avoid issues before they start.
Respectful and private women’s health services for every stage of life, covering wellness exams, hormone care, and more.
Compassionate support from a mental health clinic you can trust, with help for stress, anxiety, depression, and emotional wellness.
At Main Street Physicians, we see you as a person, not just a patient. With Dr. Christopher R. DeAngelis, our team brings over 20 years of experience in internal medicine and a deep commitment to care that’s honest, consistent, and focused on your needs. We take time to understand what matters to you. Whether it’s same-day acute care, routine preventive checkups, or help with chronic disease management, our approach always centers on your comfort and confidence in your care.
Here's why choose us,
With 20+ years in internal medicine, Dr. Christopher R. DeAngelis leads a team known for treating the whole person, not just the problem.
Your care is shaped around your real life. From preventive visits to managing chronic conditions, we build plans that actually work for you.
We’re ranked in the top 10% by Blue Cross Blue Shield of Michigan and we work hard to keep it that way.
Need to be seen fast? We offer same-day visits plus strong preventive health care that keeps you on track over time.
We don’t just send you off to someone else. We follow up, we coordinate, and we stay involved in your care every step of the way.
Please do not submit any Protected Health Information (PHI).
Warm, skilled, and professional providers who are here to support your health with real care and personal attention.
D.O., F.A.C.O.I.
Dr. Christopher DeAngelis was born in Trenton, Michigan. He received his bachelor’s degree from Emory University in Atlanta, Georgia, completed premedical studies at the University of Michigan-Dearborn, and attended four years of medical school at Midwestern University, Chicago College of Osteopathic Medicine in Downers Grove, Illinois. He then completed a three-year internship and residency in internal medicine at Henry Ford Riverside Osteopathic Hospital.
Dr. DeAngelis is board certified in internal medicine and a fellow of the American College of Osteopathic Internists. He stays current and maintains his board certification through ongoing continuing medical education, medical conferences, and reviewing the medical literature.
Our patients say it best; their honest words reflect the care, trust, and lasting support they’ve found in our practice.
Christine Morabito2025-05-23Trustindex verifies that the original source of the review is Google. Great staff from the time you check in to the time you leave Dr DeAngelis takes his time to go over everything with you. Pleasant office would recommend to anyone looking for a wonderful Dr’s office Edsel Trenton2025-05-01Trustindex verifies that the original source of the review is Google. Dr. DeAngelis and the team at MainStreet Physicians have been nothing but exceptional throughout the many years I’ve been under their care. Don’t be misled by some of the negative reviews—this is a practice that values honesty, professionalism, and patient outcomes above sugarcoating. Dr. DeAngelis tells you the truth, even when it’s hard to hear, and that’s exactly what a good doctor should do. If you're open-minded and actually listen, you’ll realize he genuinely cares and backs it up with a high level of expertise. They’re also ahead of the curve with technology—using systems like MyChart makes it incredibly easy to access test results, review your health history, send messages, manage prescriptions, and book appointments. To those complaining about bedside manner: being direct isn’t the same as being rude. I’d rather have a doctor who’s honest and effective than one who tells me what I want to hear. Highly recommend this practice. Jason Rucker2025-05-01Trustindex verifies that the original source of the review is Google. I have been seeing Dr. DeAngelis for about 20 years, I believe, I am turning 43 in 2025. Some of these bad reviews on here, please take with a grain of salt. I kind of feel as if we grew up together in a weird way. Dr. De is an amazing person and doctor. Sure, he may be honest and blunt, but that is what you want from your doctor. Sugar coating doesnt help. Plus he isnt a "pill-pusher" like other doctors. He takes a look at the whole picture and sees what else can we/he do to solve whichever issue the patient is having. Dr. De is professional, caring, honest, and truthful. Sometimes people get offended due to the truth hurts. However, at the end of the day, you, as a patient, have the option to go see another doctor for a second opinion. He isnt a God, which means he isnt perfect, but I would and have trusted him with my life for over 20 years. His staff, past and present, have always been super friendly and helpful to me. From office/desk staff to the nurses to office manager(s). Dr. DeAngelis and his team are great team. Plus he uses MyChart and cares about technology and innovation to better serve us patients. Which in turn makes things much more efficient when you go to the hospital or other doctors that use the same system. It is a hidden gem of a blessing for sure! I value my time as his patient over the years, sure we have had our disagreements, who doesn't with that much time. Most of the time we end up coming to an understanding because he will educate you if you ask or if it is outside his scope of practice will refer you to someone whom can. Dr. DeAngelis has indirectly saved my life more times than I can count. Everytime I take his advise, I become healthier and even get my medications reduced or able to come off of the meds, so I should probably listen to him more. haha. Thanks Dr. DeAngelis and the entire MainStreet Team. Keep up the amazing patient care. Sherise C2025-02-17Trustindex verifies that the original source of the review is Google. I would highly recommend Main Street Physicians to anyone looking for a Doctor/ Nurse Practitioner. Dr Deangelis and NP Jennifer has an amazing friendly staff. They don’t make you feel rushed and they take time to answer any questions you may have. Thank you Main Street Physicians 2/17/25- I would also like to add how they went above and beyond to help me find medication that my insurance covered and they never gave up. I know I must’ve got on their nerves because I was getting on my own nerves lol but every message they were empathetic and searching for a solution. I absolutely love my Doctor’s office and everyone that is there. Diane Musa2025-01-30Trustindex verifies that the original source of the review is Google. The Doctors and staff are the best. I see Jenny, NP and feel like I get the best care. Never leave without my questions being answered. Referred my family to this office. Gail Shastal2024-07-18Trustindex verifies that the original source of the review is Google. I've been only go in there a few months I'm really happy with Dr DeAngelis and his staff. They are very helpful and friendly. Todd Kolby2024-06-02Trustindex verifies that the original source of the review is Google. I have been visiting this office for a few years and I feel it is time to commend the office staff, Particularly Alicia and Breanna. They both are caring and extremely friendly in nature. I always feel very welcomed and they can make visiting the doctor pleasurable! Tom K.