Internal Medicine Doctors Near Southgate, MI
If you’ve been searching for an internal medicine physician near Southgate, MI who truly listens, explains, and guides you through every step of your health journey, Main Street Physicians P.C., is here to help. We’re proud to serve residents near Southgate with compassionate internal medicine and primary care that focuses on prevention, wellness, and lasting relationships.
Local Care That Puts You First
Good healthcare isn’t just about treatments, it’s about trust. Our patients near Southgate appreciate that they’re never rushed, always heard, and treated with genuine respect. Led by Dr. Christopher R. DeAngelis, our internal medicine doctors near Southgate, MI combine over two decades of experience with a people-first approach that values your comfort and long-term well-being.
From the first visit, our team makes it a priority to understand your goals, answer your questions, and guide you toward better health, one step at a time.



Comprehensive Services for Every Stage of Life
Your health evolves, and so should your care. Whether you’re managing a chronic illness, seeking preventive care, or needing a reliable doctor for annual checkups, our internists near Southgate provide the continuity and expertise you deserve.
Our Dedicated Services
At Main Street Physicians P.C., we offer comprehensive internal medicine and primary care services near Southgate, including preventive care, chronic disease management, women’s health services, and mental health support. Our internal medicine doctors deliver compassionate, patient-focused care designed to keep you healthy, informed, and supported through every stage of life.
Here’s what we offer to patients in and around Southgate.
Acute Disease Management
Prompt diagnosis and effective treatment for colds, infections, flu, and other common illnesses to help you recover quickly.
Chronic Disease Management
Personalized plans for conditions like diabetes, hypertension, and heart disease are focused on maintaining stability and preventing complications.
Annual Wellness Exams
Comprehensive checkups designed to monitor progress, detect concerns early, and keep your health on track year after year.
Preventive Care
Proactive care with screenings, lifestyle counseling, and immunizations that reduce risks and protect your long-term wellness.
Women's Health Care
Confidential and compassionate care for every stage of life, including hormonal balance, reproductive health, and wellness exams.
Mental Health Care
Integrated care for anxiety, depression, and stress-related conditions because emotional wellness is essential to overall health.
Ready to Take the Next Step?
Your health deserves attention, not delay. Whether it’s your first visit or you’re seeking ongoing support for chronic care, our team is here to help. Schedule your appointment today and experience why so many Southgate, MI residents choose Main Street Physicians P.C., for dependable internal medicine and primary care services.
Why Southgate, MI Families Choose Us
At Main Street Physicians P.C., we’ve built lasting relationships with patients throughout the Downriver area by offering thoughtful, consistent, and trustworthy care. Here’s what sets our clinic apart when you’re searching for an internal medicine physician near Southgate, MI:
Trusted Experience
Dr. DeAngelis brings more than 20 years of internal medicine experience, caring for patients with dedication and skill.
Personalized Attention
Every patient receives individualized guidance and medical planning that fits their lifestyle, values, and goals.
Easy Access to Care
With same-day visits, virtual appointments, and 24/7 portal access, you can reach your care team whenever you need them.
Respected Reputation
Recognized among the top 10% by Blue Cross Blue Shield of Michigan, we deliver the quality care families trust.
Serving Southgate, MI and Nearby Areas
Our main office in Woodhaven proudly serves patients from Southgate and surrounding communities who value attentive, patient-centered healthcare. Whether you’ve been looking for reliable internists near Southgate or a trusted Primary Care clinic close to home, Main Street Physicians P.C., is just a short drive away, offering consistent, connected, and compassionate care.
Meet Our Doctors
Warm, skilled, and professional providers who are here to support your health with real care and personal attention.
Christopher R. DeAngelis
D.O., F.A.C.O.I.
Dr. Christopher DeAngelis was born in Trenton, Michigan. He received his bachelor’s degree from Emory University in Atlanta, Georgia, completed premedical studies at the University of Michigan-Dearborn, and attended four years of medical school at Midwestern University, Chicago College of Osteopathic Medicine in Downers Grove, Illinois. He then completed a three-year internship and residency in internal medicine at Henry Ford Riverside Osteopathic Hospital.
Dr. DeAngelis is board certified in internal medicine and a fellow of the American College of Osteopathic Internists. He stays current and maintains his board certification through ongoing continuing medical education, medical conferences, and reviewing the medical literature.
Our Happy Patients
Our patients say it best; their honest words reflect the care, trust, and lasting support they’ve found in our practice.
Posted on Christine MorabitoTrustindex verifies that the original source of the review is Google. Great staff from the time you check in to the time you leave Dr DeAngelis takes his time to go over everything with you. Pleasant office would recommend to anyone looking for a wonderful Dr’s officePosted on Edsel TrentonTrustindex verifies that the original source of the review is Google. Dr. DeAngelis and the team at MainStreet Physicians have been nothing but exceptional throughout the many years I’ve been under their care. Don’t be misled by some of the negative reviews—this is a practice that values honesty, professionalism, and patient outcomes above sugarcoating. Dr. DeAngelis tells you the truth, even when it’s hard to hear, and that’s exactly what a good doctor should do. If you're open-minded and actually listen, you’ll realize he genuinely cares and backs it up with a high level of expertise. They’re also ahead of the curve with technology—using systems like MyChart makes it incredibly easy to access test results, review your health history, send messages, manage prescriptions, and book appointments. To those complaining about bedside manner: being direct isn’t the same as being rude. I’d rather have a doctor who’s honest and effective than one who tells me what I want to hear. Highly recommend this practice.Posted on Jason RuckerTrustindex verifies that the original source of the review is Google. I have been seeing Dr. DeAngelis for about 20 years, I believe, I am turning 43 in 2025. Some of these bad reviews on here, please take with a grain of salt. I kind of feel as if we grew up together in a weird way. Dr. De is an amazing person and doctor. Sure, he may be honest and blunt, but that is what you want from your doctor. Sugar coating doesnt help. Plus he isnt a "pill-pusher" like other doctors. He takes a look at the whole picture and sees what else can we/he do to solve whichever issue the patient is having. Dr. De is professional, caring, honest, and truthful. Sometimes people get offended due to the truth hurts. However, at the end of the day, you, as a patient, have the option to go see another doctor for a second opinion. He isnt a God, which means he isnt perfect, but I would and have trusted him with my life for over 20 years. His staff, past and present, have always been super friendly and helpful to me. From office/desk staff to the nurses to office manager(s). Dr. DeAngelis and his team are great team. Plus he uses MyChart and cares about technology and innovation to better serve us patients. Which in turn makes things much more efficient when you go to the hospital or other doctors that use the same system. It is a hidden gem of a blessing for sure! I value my time as his patient over the years, sure we have had our disagreements, who doesn't with that much time. Most of the time we end up coming to an understanding because he will educate you if you ask or if it is outside his scope of practice will refer you to someone whom can. Dr. DeAngelis has indirectly saved my life more times than I can count. Everytime I take his advise, I become healthier and even get my medications reduced or able to come off of the meds, so I should probably listen to him more. haha. Thanks Dr. DeAngelis and the entire MainStreet Team. Keep up the amazing patient care.Posted on Sherise CTrustindex verifies that the original source of the review is Google. I would highly recommend Main Street Physicians to anyone looking for a Doctor/ Nurse Practitioner. Dr Deangelis and NP Jennifer has an amazing friendly staff. They don’t make you feel rushed and they take time to answer any questions you may have. Thank you Main Street Physicians 2/17/25- I would also like to add how they went above and beyond to help me find medication that my insurance covered and they never gave up. I know I must’ve got on their nerves because I was getting on my own nerves lol but every message they were empathetic and searching for a solution. I absolutely love my Doctor’s office and everyone that is there.Posted on Diane MusaTrustindex verifies that the original source of the review is Google. The Doctors and staff are the best. I see Jenny, NP and feel like I get the best care. Never leave without my questions being answered. Referred my family to this office.Posted on Gail ShastalTrustindex verifies that the original source of the review is Google. I've been only go in there a few months I'm really happy with Dr DeAngelis and his staff. They are very helpful and friendly.Posted on Todd KolbyTrustindex verifies that the original source of the review is Google. I have been visiting this office for a few years and I feel it is time to commend the office staff, Particularly Alicia and Breanna. They both are caring and extremely friendly in nature. I always feel very welcomed and they can make visiting the doctor pleasurable! Tom K.
Frequently Asked Questions
Yes, many of our patients are from Southgate. Our clinic is nearby, making high-quality internal medicine care easy to access.
Yes, same-day appointments are available for urgent or time-sensitive concerns.
We offer preventive care, chronic disease management, women’s health, and mental health support for adults of all ages.
Absolutely, we provide secure virtual visits so you can connect with your doctor from the comfort of home.
Yes, we’re welcoming new patients from Southgate and nearby communities seeking personalized, reliable internal medicine care.
Dr. DeAngelis maintains hospital privileges at Corewell Hospital Trenton, ensuring seamless and coordinated care if hospitalization is ever needed.
Let’s Get You the Care You Need
Please do not submit any Protected Health Information (PHI).