Internal Medicine Doctors Near Trenton, MI
Finding a doctor who truly listens and takes the time to understand your health can feel overwhelming. If you’ve been searching for an Internal Medicine Physician Near Trenton, MI you don’t have to look far. At Main Street Physicians, we proudly serve patients from Trenton, MI and nearby communities with thoughtful, reliable care that’s built around you.
Local Team That Feels Like Family
Choosing the right doctor isn’t just about convenience; it’s about finding someone who makes you feel at ease, explains things clearly, and partners with you in every step of your health journey. That’s exactly what our patients near Trenton, MI experience.
With over 20 years of hands-on experience, Dr. Christopher R. DeAngelis and our team of Internal Medicine Doctors Near Trenton, MI offer a down-to-earth, personal approach. We care for the whole person, not just the condition, making sure every visit feels like a conversation, not a rushed appointment.



Comprehensive Services for Every Stage of Life
Life can be unpredictable, and health needs often change along the way. Whether you’re managing a chronic condition or simply keeping up with annual checkups, our internists make sure you have the support and answers you need.
Here’s what we provide for families in and around Trenton, MI:
Acute Disease Management
For sudden illnesses like colds, flu, or infections, providing fast relief and treatment so you can get back to feeling healthy quickly.
Chronic Disease Management
For diabetes, hypertension, and heart disease, with personalized care plans that help you stay in control and improve daily quality of life.
Annual Wellness Exams
Act as your yearly health check-in, tracking progress, spotting issues early, and giving you clear guidance for healthier living every year.
Preventive Care
With screenings, vaccines, and tailored lifestyle advice that help reduce risks, avoid potential health problems, and keep you feeling your best.
Women's Health Care
Services include wellness exams, reproductive care, and hormone replacement provided in a respectful, supportive, and private environment for every stage of life.
Mental Health Care
For anxiety, depression, ADHD, and more, offering compassionate care that addresses emotional well-being as an essential part of overall health.
No matter what brings you in, our Internists near Trenton, MI, focus on making healthcare less stressful and more meaningful.
Ready to Get Started?
Your health is too important to put off. Whether it’s a routine wellness visit, managing a long-term condition, or simply getting a trusted opinion, our team is here for you. Schedule your first appointment today and see why so many in Trenton, MI already call Main Street Physicians their medical home.
Why Trenton, MI Families Choose Us
Patients across the Downriver area turn to us because we’re not just doctors, we’re neighbors who understand the community we serve. Here’s why many choose us when looking for an Internal Medicine Physician Near Trenton:
Experience You Can Trust
Dr. DeAngelis has more than two decades of experience caring for patients in internal medicine.
Personalized Care
We listen first, then build care plans around your real-life needs, not just test results.
Convenient Access
Same-day appointments, telehealth visits, and 24/7 access to your medical chart mean care is always within reach.
Trusted Reputation
Ranked in the top 10% by Blue Cross Blue Shield of Michigan, we’re committed to maintaining care you can count on.
Serving Trenton, MI and Nearby Communities
Even though our office is based in Woodhaven, many families from Trenton rely on us for consistent, high-quality care. If you’ve been searching online for an Internal Medicine clinic in Woodhaven or reliable Internists near Trenton, MI, our practice is just a short drive away from Allen Park, Dearborn, Downriver and other communities.
Meet Our Doctors
Warm, skilled, and professional providers who are here to support your health with real care and personal attention.
Christopher R. DeAngelis
D.O., F.A.C.O.I.
Dr. Christopher DeAngelis was born in Trenton, Michigan. He received his bachelor’s degree from Emory University in Atlanta, Georgia, completed premedical studies at the University of Michigan-Dearborn, and attended four years of medical school at Midwestern University, Chicago College of Osteopathic Medicine in Downers Grove, Illinois. He then completed a three-year internship and residency in internal medicine at Henry Ford Riverside Osteopathic Hospital.
Dr. DeAngelis is board certified in internal medicine and a fellow of the American College of Osteopathic Internists. He stays current and maintains his board certification through ongoing continuing medical education, medical conferences, and reviewing the medical literature.
Our Happy Patients
Our patients say it best; their honest words reflect the care, trust, and lasting support they’ve found in our practice.
Posted on Christine MorabitoTrustindex verifies that the original source of the review is Google. Great staff from the time you check in to the time you leave Dr DeAngelis takes his time to go over everything with you. Pleasant office would recommend to anyone looking for a wonderful Dr’s officePosted on Edsel TrentonTrustindex verifies that the original source of the review is Google. Dr. DeAngelis and the team at MainStreet Physicians have been nothing but exceptional throughout the many years I’ve been under their care. Don’t be misled by some of the negative reviews—this is a practice that values honesty, professionalism, and patient outcomes above sugarcoating. Dr. DeAngelis tells you the truth, even when it’s hard to hear, and that’s exactly what a good doctor should do. If you're open-minded and actually listen, you’ll realize he genuinely cares and backs it up with a high level of expertise. They’re also ahead of the curve with technology—using systems like MyChart makes it incredibly easy to access test results, review your health history, send messages, manage prescriptions, and book appointments. To those complaining about bedside manner: being direct isn’t the same as being rude. I’d rather have a doctor who’s honest and effective than one who tells me what I want to hear. Highly recommend this practice.Posted on Jason RuckerTrustindex verifies that the original source of the review is Google. I have been seeing Dr. DeAngelis for about 20 years, I believe, I am turning 43 in 2025. Some of these bad reviews on here, please take with a grain of salt. I kind of feel as if we grew up together in a weird way. Dr. De is an amazing person and doctor. Sure, he may be honest and blunt, but that is what you want from your doctor. Sugar coating doesnt help. Plus he isnt a "pill-pusher" like other doctors. He takes a look at the whole picture and sees what else can we/he do to solve whichever issue the patient is having. Dr. De is professional, caring, honest, and truthful. Sometimes people get offended due to the truth hurts. However, at the end of the day, you, as a patient, have the option to go see another doctor for a second opinion. He isnt a God, which means he isnt perfect, but I would and have trusted him with my life for over 20 years. His staff, past and present, have always been super friendly and helpful to me. From office/desk staff to the nurses to office manager(s). Dr. DeAngelis and his team are great team. Plus he uses MyChart and cares about technology and innovation to better serve us patients. Which in turn makes things much more efficient when you go to the hospital or other doctors that use the same system. It is a hidden gem of a blessing for sure! I value my time as his patient over the years, sure we have had our disagreements, who doesn't with that much time. Most of the time we end up coming to an understanding because he will educate you if you ask or if it is outside his scope of practice will refer you to someone whom can. Dr. DeAngelis has indirectly saved my life more times than I can count. Everytime I take his advise, I become healthier and even get my medications reduced or able to come off of the meds, so I should probably listen to him more. haha. Thanks Dr. DeAngelis and the entire MainStreet Team. Keep up the amazing patient care.Posted on Sherise CTrustindex verifies that the original source of the review is Google. I would highly recommend Main Street Physicians to anyone looking for a Doctor/ Nurse Practitioner. Dr Deangelis and NP Jennifer has an amazing friendly staff. They don’t make you feel rushed and they take time to answer any questions you may have. Thank you Main Street Physicians 2/17/25- I would also like to add how they went above and beyond to help me find medication that my insurance covered and they never gave up. I know I must’ve got on their nerves because I was getting on my own nerves lol but every message they were empathetic and searching for a solution. I absolutely love my Doctor’s office and everyone that is there.Posted on Diane MusaTrustindex verifies that the original source of the review is Google. The Doctors and staff are the best. I see Jenny, NP and feel like I get the best care. Never leave without my questions being answered. Referred my family to this office.Posted on Gail ShastalTrustindex verifies that the original source of the review is Google. I've been only go in there a few months I'm really happy with Dr DeAngelis and his staff. They are very helpful and friendly.Posted on Todd KolbyTrustindex verifies that the original source of the review is Google. I have been visiting this office for a few years and I feel it is time to commend the office staff, Particularly Alicia and Breanna. They both are caring and extremely friendly in nature. I always feel very welcomed and they can make visiting the doctor pleasurable! Tom K.
Frequently Asked Questions
Yes, many Trenton residents visit us. We’re close by, making access to trusted internal medicine care simple and convenient.
We treat colds, infections, diabetes, hypertension, heart disease, anxiety, depression, and provide preventive care designed to your unique needs.
Yes, we offer same-day appointments for urgent concerns, ensuring you get timely care without unnecessary waiting or delays.
Absolutely, Dr. DeAngelis cares for his patients at Corewell Hospital Trenton, ensuring continuity and personal oversight during hospital stays.
We combine decades of experience, compassionate care, and community connection, focusing on your whole health, not just medical conditions.
Yes, we provide virtual visits, giving you convenient access to medical advice and follow-ups from the comfort of home.
Let’s Get You the Care You Need
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